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Applied Medical Informatics for the Chest Physician
In the first installment in this series on applied medical informatics (AMI) for the chest physician, we reviewed the structure and basic function of the electronic medical record (EMR). Even to the casual observer of the technology of the EMR in American medicine, the following two realities are manifest: (1) recently, there has been a […]
Pulmonary Mycobacterium kansasii Infection in Israel, 1999-2004: Conclusion
The present report supports M kansasii susceptibility to clarithromycin and ofloxacin.2′ Ofloxacin was also superior to ciprofloxacin (Table 2). We believed that some isolates are susceptible to slightly higher ciprofloxacin concentrations; therefore, when clinically indicated, ciprofloxacin should be used regardless of the in vitro susceptibility results. M kansasii infection affects middle-aged men more than women. […]
Pulmonary Mycobacterium kansasii Infection in Israel, 1999-2004: Discussion
We noted several clinically significant findings. Series from the United States’ and Spain suggested a higher-than-normal rate of isolation of M kansasii from HIV-positive patients, and a study done between 1981 and 1987 reported a 200-fold higher incidence of disseminated M kansasii infection in people with AIDS (138 per 100,000) than in the general population […]
Pulmonary Mycobacterium kansasii Infection in Israel, 1999-2004: Molecular Characterizations
Twenty M kansasii isolates underwent molecular characterization. Eighteen isolates were found to be M kansasii type I, and 2 isolates were M kansasii type II. Table 2 summarizes the drug sensitivity of the M kansasii isolates. All isolates were sensitive to rifam-picin, all but one isolate (borderline) were sensitive to ethambutol and ofloxacin, and all […]
Pulmonary Mycobacterium kansasii Infection in Israel, 1999-2004: Statistical Analysis
Data on clinical features of the patients (including systemic comorbid disease and smoking status), radiologic findings, treatment, and outcome were obtained from the case notes and laboratory records by a single investigator. Chest radiographs obtained within 2 weeks of diagnosis of mycobacterial disease were read by an independent investigator who was blinded to the clinical […]
Pulmonary Mycobacterium kansasii Infection in Israel, 1999-2004: Materials and Methods
The study sample included 56 patients with a diagnosis of M kansasii lung infection who attended the tuberculosis centers in Tel Aviv and Rehovot, Israel, from April 1999 to April 2004. The diagnosis was based on the guidelines of the ATS, namely appropriate symptomatology, compatible radiographic abnormalities, and multiple culture-positive respiratory specimens for M kansasii.15 […]
Pulmonary Mycobacterium kansasii Infection in Israel, 1999-2004
Mycobacterium kansasii has traditionally been considered the most virulent of the nontuber-culous mycobacteria.,2 It is the second most common nontuberculous mycobacterium after Mycobacterium avium complex3 and the most common cause of nontuberculous mycobacterial lung disease in the United Kingdom and Western Europe. Infection with M kansasii probably occurs via an aerosol route, Tap water is […]